A validated lineage-derived somatic truth data set enables benchmarking in cancer genome analysis

Existing cancer benchmark data sets for human sequencing data use germline variants, synthetic methods, or expensive validations, none of which are satisfactory for providing a large collection of true somatic variation across a whole genome. Here we propose a data set, Lineage derived Somatic Truth...

Full description

Bibliographic Details
Main Authors: Shand, Megan (Author), Soto, Jose (Author), Lichtenstein, Lee (Author), Benjamin, David (Author), Farjoun, Yossi (Author), Brody, Yehuda (Author), Maruvka, Yosef (Author), Blainey, Paul C. (Author), Banks, Eric (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Springer Science and Business Media LLC, 2022-02-09T16:06:34Z.
Subjects:
Online Access:Get fulltext