A 3D microvascular network model to study the impact of hypoxia on the extravasation potential of breast cell lines

© 2018, The Author(s). Hypoxia is a common feature of the tumor microenvironment. Accumulating evidence has demonstrated hypoxia to be an important trigger of tumor cell invasion or metastasizes via hypoxia-signaling cascades, including hypoxia-inducible factors (HIFs). Microfluidic model can be a r...

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Bibliographic Details
Main Authors: Song, Jiho (Author), Miermont, Agnès (Author), Lim, Chwee-Teck (Author), Kamm, Roger Dale (Author)
Other Authors: Singapore-MIT Alliance in Research and Technology (SMART) (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor)
Format: Article
Language:English
Published: Springer Nature, 2022-04-14T16:08:49Z.
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