CoCoA-diff: counterfactual inference for single-cell gene expression analysis
Abstract Finding a causal gene is a fundamental problem in genomic medicine. We present a causal inference framework, CoCoA-diff, that prioritizes disease genes by adjusting confounders without prior knowledge of control variables in single-cell RNA-seq data. We demonstrate that our method substanti...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer Science and Business Media LLC,
2022-05-18T15:41:51Z.
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| Subjects: | |
| Online Access: | Get fulltext |