mGluR5 Negative Modulators for Fragile X: Treatment Resistance and Persistence
<jats:p>Fragile X syndrome (FXS) is caused by silencing of the human <jats:italic>FMR1</jats:italic> gene and is the leading monogenic cause of intellectual disability and autism. Abundant preclinical data indicated that negative allosteric modulators (NAMs) of metabotropic glutama...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media SA,
2021-11-03T15:52:53Z.
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| Subjects: | |
| Online Access: | Get fulltext |