Decreasing mitochondrial RNA polymerase activity reverses biased inheritance of hypersuppressive mtDNA
<jats:p>Faithful inheritance of mitochondrial DNA (mtDNA) is crucial for cellular respiration/oxidative phosphorylation and mitochondrial membrane potential. However, how mtDNA is transmitted to progeny is not fully understood. We utilized hypersuppressive mtDNA, a class of respiratory deficie...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS),
2021-11-12T14:41:10Z.
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| Subjects: | |
| Online Access: | Get fulltext |