Microglia enable mature perineuronal nets disassembly upon anesthetic ketamine exposure or 60-Hz light entrainment in the healthy brain

Perineuronal nets (PNNs), components of the extracellular matrix, preferentially coat parvalbumin-positive interneurons and constrain critical-period plasticity in the adult cerebral cortex. Current strategies to remove PNN are long-lasting, invasive, and trigger neuropsychiatric symptoms. Here, we...

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Bibliographic Details
Main Authors: Venturino, Alessandro (Author), Schulz, Rouven (Author), De Jesús-Cortés, Héctor (Author), Maes, Margaret E (Author), Nagy, Bálint (Author), Reilly-Andújar, Francis (Author), Colombo, Gloria (Author), Cubero, Ryan John A (Author), Schoot Uiterkamp, Florianne E (Author), Bear, Mark F (Author), Siegert, Sandra (Author)
Format: Article
Language:English
Published: Elsevier BV, 2021-11-19T15:25:50Z.
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