Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma

<jats:title>Abstract</jats:title><jats:p>Diffuse large B-cell lymphoma (DLBCL) is the most common type of aggressive lymphoid malignancy and a highly heterogeneous disease. In this study, we performed whole-genome and transcriptome sequencing, and a genome-wide CRISPR-Cas9-knockout...

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Main Authors: Nie, Man (Author), Du, Likun (Author), Ren, Weicheng (Author), Joung, Julia (Author), Ye, Xiaofei (Author), Shi, Xi (Author), Ciftci, Sibel (Author), Liu, Dongbing (Author), Wu, Kui (Author), Zhang, Feng (Author), Pan-Hammarström, Qiang (Author)
Format: Article
Language:English
Published: Springer Science and Business Media LLC, 2021-12-08T18:31:23Z.
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