T Follicular Regulatory Cell-Derived Fibrinogen-like Protein 2 Regulates Production of Autoantibodies and Induction of Systemic Autoimmunity

T Follicular Regulatory Cell-Derived Fibrinogen-like Protein 2 Regulates Production of Autoantibodies and Induction of Systemic Autoimmunity

© 2020 by The American Association of Immunologists, Inc. T follicular regulatory (TFR) cells limit Ab responses, but the underlying mechanisms remain largely unknown. In this study, we identify Fgl2 as a soluble TFR cell effector molecule through single-cell gene expression profiling. Highly expres...

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Main Authors: Sungnak, Waradon (Author), Wagner, Allon (Author), Kowalczyk, Monika S (Author), Bod, Lloyd (Author), Kye, Yoon-Chul (Author), Sage, Peter T (Author), Sharpe, Arlene H (Author), Sobel, Raymond A (Author), Quintana, Francisco J (Author), Rozenblatt-Rosen, Orit (Author), Regev, Aviv (Author), Wang, Chao (Author), Yosef, Nir (Author), Kuchroo, Vijay K (Author)
Format: Article
Language:English
Published: The American Association of Immunologists, 2021-12-16T13:57:02Z.
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