The Ups and Downs of the Striatum: Dopamine Biases Upstate Balance of Striosomes and Matrix

© 2020 Elsevier Inc. Prager et al. demonstrate an opposite regulation of activity in striosomes and matrix of the striatum. By a D1-receptor-linked L-VGCC-dependent mechanism, dopamine release can extend upstates in matrix D1-expressing projection neurons (dSPNs) but shorten them in striosomal dSPNs...

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Bibliographic Details
Main Authors: Graybiel, Ann M (Author), Matsushima, Ayano (Author)
Other Authors: McGovern Institute for Brain Research at MIT (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2021-12-16T18:27:31Z.
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