Antibody screening at reduced pH enables preferential selection of potently neutralizing antibodies targeting SARS‐CoV ‐2

Antibody screening at reduced pH enables preferential selection of potently neutralizing antibodies targeting SARS‐CoV ‐2

Antiviral monoclonal antibody (mAb) discovery enables the development of antibody-based antiviral therapeutics. Traditional antiviral mAb discovery relies on affinity between antibody and a viral antigen to discover potent neutralizing antibodies, but these approaches are inefficient because many hi...

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Main Authors: Madan, Bharat (Author), Reddem, Eswar R. (Author), Wang, Pengfei (Author), Casner, Ryan G. (Author), Nair, Manoj S. (Author), Huang, Yaoxing (Author), Fahad, Ahmed S. (Author), Souza, Matheus Oliveira (Author), Banach, Bailey B. (Author), López Acevedo, Sheila N. (Author), Pan, Xiaoli (Author), Nimrania, Rajani (Author), Teng, I‐Ting (Author), Bahna, Fabiana (Author), Zhou, Tongqing (Author), Zhang, Baoshan (Author), Yin, Michael T. (Author), Ho, David D. (Author), Kwong, Peter D. (Author), Shapiro, Lawrence (Author), DeKosky, Brandon J. (Author)
Format: Article
Language:English
Published: Wiley, 2022-02-14T16:53:01Z.
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