Evidence for Simultaneous Dearomatization of Two Aromatic Rings under Mild Conditions in Cu(I)-Catalyzed Direct Asymmetric Dearomatization of Pyridine

© 2020 American Chemical Society. Bis(phosphine) copper hydride complexes are uniquely able to catalyze direct dearomatization of unactivated pyridines with carbon nucleophiles, but the mechanistic basis for this result has been unclear. Here we show that, contrary to our initial hypotheses, the cat...

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Bibliographic Details
Main Authors: Gribble, Michael W. (Author), Liu, Richard Y. (Author), Buchwald, Stephen L. (Author)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2022-02-14T18:50:08Z.
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