A Concise Route to MK-4482 (EIDD-2801) from Cytidine: Part 2
A new route to MK-4482 was developed. The route replaces uridine with the more available and less expensive cytidine. Low-cost, simple reagents are used for the chemical transformations, and the yield is improved from 17% to 44%. A step is removed from the longest linear sequence, and these advancem...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Georg Thieme Verlag KG,
2022-03-23T13:51:22Z.
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| Subjects: | |
| Online Access: | Get fulltext |