Geminal repulsion disrupts Diels-Alder reactions of geminally substituted cyclopentadienes and 4H-pyrazoles
We have experimentally and computationally explored the sluggish Diels-Alder reactivities of the geminally substituted 5,5-dimethylcyclopentadiene and 5,5-dimethyl-2,3-diazacyclopentadiene (4,4-dimethyl-4H-pyrazole) scaffolds. We found that geminal dimethylation of 1,2,3,4-tetramethylcyclopentadiene...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier BV,
2022-04-11T19:52:27Z.
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| Subjects: | |
| Online Access: | Get fulltext |