Multiscale modeling of genome organization with maximum entropy optimization

Three-dimensional (3D) organization of the human genome plays an essential role in all DNA-templated processes, including gene transcription, gene regulation, and DNA replication. Computational modeling can be an effective way of building high-resolution genome structures and improving our understan...

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Bibliographic Details
Main Authors: Lin, Xingcheng (Author), Qi, Yifeng (Author), Latham, Andrew P (Author), Zhang, Bin (Author)
Format: Article
Language:English
Published: AIP Publishing, 2022-03-23T16:27:35Z.
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