A dual role for H2A.Z.1 in modulating the dynamics of RNA polymerase II initiation and elongation

RNA polymerase II (RNAPII) pausing immediately downstream of the transcription start site is a critical rate-limiting step for the expression of most metazoan genes. During pause release, RNAPII encounters a highly conserved +1 H2A.Z nucleosome, yet how this histone variant contributes to transcript...

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Bibliographic Details
Main Authors: Mylonas, Constantine (Author), Lee, Choongman (Author), Auld, Alexander L (Author), Cisse, Ibrahim I (Author), Boyer, Laurie A (Author)
Format: Article
Language:English
Published: Springer Science and Business Media LLC, 2022-04-01T12:08:58Z.
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