A dual role for H2A.Z.1 in modulating the dynamics of RNA polymerase II initiation and elongation
RNA polymerase II (RNAPII) pausing immediately downstream of the transcription start site is a critical rate-limiting step for the expression of most metazoan genes. During pause release, RNAPII encounters a highly conserved +1 H2A.Z nucleosome, yet how this histone variant contributes to transcript...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Springer Science and Business Media LLC,
2022-04-01T12:08:58Z.
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Subjects: | |
Online Access: | Get fulltext |