Significant Sparse Polygenic Risk Scores across 813 traits in UK Biobank
We present a systematic assessment of polygenic risk score (PRS) prediction across more than 1,500 traits using genetic and phenotype data in the UK Biobank. We report 813 sparse PRS models with significant (p < 2.5 x 10−5) incremental predictive performance when compared against the covariate-on...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Cold Spring Harbor Laboratory,
2022-05-23T15:38:08Z.
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| Subjects: | |
| Online Access: | Get fulltext |