Synthetic Circuit-Driven Expression of Heterologous Enzymes for Disease Detection

The integration of nanotechnology and synthetic biology could lay the framework for new classes of engineered biosensors that produce amplified readouts of disease states. As a proof-of-concept demonstration of this vision, here we present an engineered gene circuit that, in response to cancer-assoc...

Full description

Bibliographic Details
Main Authors: He, Jiang (Author), Nissim, Lior (Author), Soleimany, Ava P (Author), Binder-Nissim, Adina (Author), Fleming, Heather E (Author), Lu, Timothy K (Author), Bhatia, Sangeeta N (Author)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2022-06-01T19:48:24Z.
Subjects:
Online Access:Get fulltext