Tissue catabolism and donor-specific dexamethasone response in a human osteochondral model of post-traumatic osteoarthritis

Abstract Background Post-traumatic osteoarthritis (PTOA) does not currently have clinical prognostic biomarkers or disease-modifying drugs, though promising candidates such as dexamethasone (Dex) exist. Many challenges in studying and treating this disease stem from tissue interactions that complica...

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Main Authors: Black, Rebecca M. (Author), Flaman, Lisa L. (Author), Lindblom, Karin (Author), Chubinskaya, Susan (Author), Grodzinsky, Alan J. (Author), Önnerfjord, Patrik (Author)
Format: Article
Language:English
Published: BioMed Central, 2022-06-13T13:44:58Z.
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