Tissue catabolism and donor-specific dexamethasone response in a human osteochondral model of post-traumatic osteoarthritis
Abstract Background Post-traumatic osteoarthritis (PTOA) does not currently have clinical prognostic biomarkers or disease-modifying drugs, though promising candidates such as dexamethasone (Dex) exist. Many challenges in studying and treating this disease stem from tissue interactions that complica...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BioMed Central,
2022-06-13T13:44:58Z.
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Subjects: | |
Online Access: | Get fulltext |