Genetic drivers of m6A methylation in human brain, lung, heart and muscle

The most prevalent post-transcriptional mRNA modification, N6-methyladenosine (m6A), plays diverse RNA-regulatory roles, but its genetic control in human tissues remains uncharted. Here we report 129 transcriptome-wide m6A profiles, covering 91 individuals and 4 tissues (brain, lung, muscle and hear...

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Main Authors: Xiong, Xushen (Author), Hou, Lei (Author), Park, Yongjin P (Author), Molinie, Benoit (Author), Ardlie, Kristin G (Author), Aguet, François (Author), Gregory, Richard I (Author), Kellis, Manolis (Author)
Format: Article
Language:English
Published: Springer Science and Business Media LLC, 2022-07-13T16:21:16Z.
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