Digital CRISPR-based method for the rapid detection and absolute quantification of nucleic acids

Rapid diagnostics of adventitious agents in biopharmaceutical/cell manufacturing release testing and the fight against viral infection have become critical. Quantitative real-time PCR and CRISPR-based methods rapidly detect DNA/RNA in 1 h but suffer from inter-site variability. Absolute quantificati...

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Bibliographic Details
Main Authors: Wu, Xiaolin (Author), Tay, Joshua K (Author), Goh, Chuan Keng (Author), Chan, Cheryl (Author), Lee, Yie Hou (Author), Springs, Stacy L (Author), Wang, De Yun (Author), Loh, Kwok Seng (Author), Lu, Timothy K (Author), Yu, Hanry (Author)
Format: Article
Language:English
Published: Elsevier BV, 2022-07-15T14:27:40Z.
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