Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation

Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation

Although 75% of endometrial cancers are treated at an early stage, 15% to 20% of these recur. We performed an integrated analysis of genome-wide expression and copy-number data for primary endometrial carcinomas with extensive clinical and histopathological data to detect features predictive of recu...

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Main Authors: Salvesen, H. B. (Author), Carter, Scott L. (Contributor), Mannelqvist, M. (Author), Dutt, Amit (Contributor), Getz, Gad (Contributor), Stefansson, I. M. (Author), Raeder, M. B. (Author), Sos, M. L. (Author), Engelsen, I. B. (Author), Trovik, J. (Author), Wik, E. (Author), Greulich, Heidi (Contributor), Bo, T. H. (Author), Jonassen, I. (Author), Thomas, R. K. (Author), Zander, T. (Author), Garraway, Levi A. (Contributor), Oyan, A. M. (Author), Sellers, W. R. (Author), Kalland, K. H. (Author), Meyerson, Matthew L. (Contributor), Akslen, L. A. (Author), Beroukhim, Rameen (Contributor)
Other Authors: Broad Institute of MIT and Harvard (Contributor), Harvard University- (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences, 2009-12-28T15:51:20Z.
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