Linking high-resolution metabolic flux phenotypes and transcriptional regulation in yeast modulated by the global regulator Gcn4p

Linking high-resolution metabolic flux phenotypes and transcriptional regulation in yeast modulated by the global regulator Gcn4p

Genome sequencing dramatically increased our ability to understand cellular response to perturbation. Integrating system-wide measurements such as gene expression with networks of protein-protein interactions and transcription factor binding revealed critical insights into cellular behavior. However...

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Main Authors: Moxley, Joel F. (Contributor), Jewett, Michael C. (Author), Antoniewicz, Maciek R. (Contributor), Villas-Boas, Silas G. (Author), Alper, Hal (Contributor), Wheeler, Robert T. (Author), Tong, Lily V. (Contributor), Hinnebusch, Alan G. (Author), Ideker, Trey (Author), Nielsen, Jens Kromann (Author), Stephanopoulos, Gregory (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Whitehead Institute for Biomedical Research (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences, 2009-12-28T16:10:44Z.
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