Integrin beta(1)-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs

The development of metastases is an extended and inefficient process involving multiple steps. The last of these involves the growth of micrometastases into macroscopic tumors. We show here that intravenously injected, nonmetastatic cancer cells cease proliferating after extravasating into the paren...

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Bibliographic Details
Main Authors: Shibue, Tsukasa (Contributor), Weinberg, Robert A (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor), Ludwig Center for Molecular Oncology (Massachusetts Institute of Technology) (Contributor), Weinberg, Robert A. (Contributor)
Format: Article
Language:English
Published: United States National Academy of Sciences, 2010-03-12T21:51:50Z.
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