Cross Species Genomic Analysis Identifies a Mouse Model as Undifferentiated Pleomorphic Sarcoma/Malignant Fibrous Histiocytoma

Cross Species Genomic Analysis Identifies a Mouse Model as Undifferentiated Pleomorphic Sarcoma/Malignant Fibrous Histiocytoma

Undifferentiated pleomorphic sarcoma/Malignant Fibrous Histiocytoma (MFH) is one of the most common subtypes of human soft tissue sarcoma. Using cross species genomic analysis, we define a geneset from the LSL-Kras[superscript G12D]; Trp53[superscript Flox/Flox] mouse model of soft tissue sarcoma th...

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Main Authors: Kirsch, David G. (Author), Mukherjee, Sayan (Author), Lev, Dina (Author), Brigman, Brian E. (Author), Yoon, Sam S. (Author), Hornicek, Francis J. (Author), Eward, William C. (Author), Stangenberg, Lars (Author), Dodd, Rebecca D. (Author), Lazar, Alexander J. (Author), Lahat, Guy (Author), Dodd, Leslie (Author), Riedel, Richard F. (Author), Mito, Jeffrey K. (Author), Jacks, Tyler E (Author)
Other Authors: Koch Institute for Integrative Cancer Research at MIT (Contributor), Jacks, Tyler E. (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2010-05-05T20:15:48Z.
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