Application of Gene Network Analysis Techniques Identifies AXIN1/PDIA2 and Endoglin Haplotypes Associated with Bicuspid Aortic Valve
Bicuspid Aortic Valve (BAV) is a highly heritable congenital heart defect. The low frequency of BAV (1% of general population) limits our ability to perform genome-wide association studies. We present the application of four a priori SNP selection techniques, reducing the multiple-testing penalty by...
| Main Authors: | , , , , , , , , |
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| Other Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science,
2010-05-13T17:58:34Z.
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| Subjects: | |
| Online Access: | Get fulltext |