Nitric oxide activation of Keap1/Nrf2 signaling in human colon carcinoma cells

Nitric oxide activation of Keap1/Nrf2 signaling in human colon carcinoma cells

The transcription factor NF-E2-related nuclear factor 2 (Nrf2) regulates expression of genes that protect cells from oxidative damage. Here, we characterized nitric oxide (•NO)-induced Nrf2-Kelch-like ECH-associated protein 1 (Keap1) signaling and its role in counteracting •NO-induced apoptosis of h...

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Bibliographic Details
Main Authors: Wogan, Gerald N. (Contributor), Trudel, Laura J. (Contributor), Thiantanawat, Apinya (Contributor), Godoy, Luiz Claudio (Contributor), Kim, Min Young (Contributor), Lia, Chun-Qi (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: United States National Academy of Sciences, 2010-05-14T18:51:21Z.
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