Antidepressant Actions of Histone Deacetylase Inhibitors

Antidepressant Actions of Histone Deacetylase Inhibitors

Persistent symptoms of depression suggest the involvement of stable molecular adaptations in brain, which may be reflected at the level of chromatin remodeling. We find that chronic social defeat stress in mice causes a transient decrease, followed by a persistent increase, in levels of acetylated h...

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Main Authors: Haggarty, Stephen J. (Contributor), Covington III, Herbert E. (Author), Maze, Ian (Author), LaPlant, Quincey C. (Author), Vialou, Vincent F. (Author), Ohnishi, Yoshinori N. (Author), Berton, Olivier (Author), Fass, Daniel M. (Author), Renthal, William (Author), Rush III, Augustus J. (Author), Wu, Emma Y. (Author), Ghose, Subroto (Author), Krishnan, Vaishnav (Author), Russo, Scott J. (Author), Tamminga, Carol (Author), Nestler, Eric J. (Author)
Other Authors: Picower Institute for Learning and Memory (Contributor)
Format: Article
Language:English
Published: Society for Neuroscience, 2010-07-15T19:31:38Z.
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