Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum

Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum

Background: The identification of genetic changes that confer drug resistance or other phenotypic changes in pathogens can help optimize treatment strategies, support the development of new therapeutic agents, and provide information about the likely function of genes. Elucidating mechanisms of phen...

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Main Authors: Dharia, Neekesh V (Author), Sidhu, Amar Bir Singh (Contributor), Cassera, Maria Belen (Author), Westenberger, Scott J (Author), Bopp, Selina ER (Author), Eastman, Rich T (Author), Plouffe, David (Author), Batalov, Serge (Author), Volkman, Sarah K (Author), Zhou, Yingyao (Author), Fidock, David A (Author), Winzeler, Elizabeth A (Author), Park, Daniel J. (Contributor), Wirth, Dyann F. (Contributor)
Other Authors: Broad Institute of MIT and Harvard (Contributor)
Format: Article
Language:English
Published: BioMed Central Ltd, 2010-10-12T18:40:51Z.
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