Large-scale identification of genetic design strategies using local search

Large-scale identification of genetic design strategies using local search

In the past decade, computational methods have been shown to be well suited to unraveling the complex web of metabolic reactions in biological systems. Methods based on flux-balance analysis (FBA) and bi-level optimization have been used to great effect in aiding metabolic engineering. These methods...

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Bibliographic Details
Main Authors: Lun, Desmond S. (Author), Rockwell, Graham (Author), Guido, Nicholas J. (Author), Baym, Michael Hartmann (Contributor), Kelner, Jonathan Adam (Contributor), Berger, Bonnie (Contributor), Galagan, James E. (Author), Church, George M. (Author)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Mathematics (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2011-02-01T13:36:48Z.
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