Expression of human cytokines dramatically improves reconstitution of specific human-blood lineage cells in humanized mice
Adoptive transfer of human hematopoietic stem cells (HSCs) into mice lacking T, B and natural killer (NK) cells leads to development of human-blood lineage cells in the recipient mice (humanized mice). Although human B cell reconstitution is robust and T cell reconstitution is reasonable in the reci...
| Main Authors: | , , |
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| Other Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
National Academy of Sciences,
2011-02-04T12:47:08Z.
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| Subjects: | |
| Online Access: | Get fulltext |