αvβ3 integrin spatially regulates VASP and RIAM to control adhesion dynamics and migration

Integrins are fundamental to the control of protrusion and motility in adherent cells. However, the mechanisms by which specific members of this receptor family cooperate in signaling to cytoskeletal and adhesion dynamics are poorly understood. Here, we show that the loss of β3 [beta 3] integrin in...

Full description

Bibliographic Details
Main Authors: Gertler, Frank (Contributor), Worth, Daniel C. (Author), Hodivala-Dilke, Kairbaan (Author), Robinson, Stephen D. (Author), King, Samantha J. (Author), Morton, Penny E. (Author), Humphries, Martin J. (Author), Parsons, Maddy (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Rockefeller University Press, 2011-02-11T22:24:35Z.
Subjects:
Online Access:Get fulltext