Ligand-dependent dynamics of retinoic acid receptor binding during early neurogenesis

Ligand-dependent dynamics of retinoic acid receptor binding during early neurogenesis

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Background: Among its many roles in development, retinoic acid determines the anterior-posterior identity of differentiating motor neurons by activating retinoic acid receptor (RAR)-mediated transcription. RAR is thought to bind the genome constitutively, and only induce transcription in the presenc...

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Bibliographic Details
Main Authors: Mahony, Shaun (Contributor), McCuine, Scott (Author), Wichterle, Hynek (Author), Gifford, David K. (Contributor), Mazzoni, Esteban O. (Author), Young, Richard A. (Author)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor)
Format: Article
Language:English
Published: BioMed Central Ltd, 2011-02-23T14:09:38Z.
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