The AAA+ ClpX machine unfolds a keystone subunit to remodel the Mu transpososome

A hyperstable complex of the tetrameric MuA transposase with recombined DNA must be remodeled to allow subsequent DNA replication. ClpX, a AAA+ enzyme, fulfills this function by unfolding one transpososome subunit. Which MuA subunit is extracted, and how complex destabilization relates to establishm...

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Bibliographic Details
Main Authors: Baker, Tania (Contributor), Abdelhakim, Aliaa H. (Contributor), Sauer, Robert T (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Sauer, Robert T. (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2011-03-01T20:16:06Z.
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