Conversion of a yeast prion protein to an infectious form in bacteria

Prions are infectious, self-propagating protein aggregates that have been identified in evolutionarily divergent members of the eukaryotic domain of life. Nevertheless, it is not yet known whether prokaryotes can support the formation of prion aggregates. Here we demonstrate that the yeast prion pro...

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Bibliographic Details
Main Authors: Lindquist, Susan (Contributor), Dong, Jijun (Contributor), Garrity, Sean J. (Author), Sivanathan, Viknesh (Author), Hochschild, Ann (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2011-03-02T17:15:51Z.
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