The Crystal Structure of a Junction Between Two Z-DNA Helices

The Crystal Structure of a Junction Between Two Z-DNA Helices

The double helix of DNA, when composed of dinucleotide purine-pyrimidine repeats, can adopt a left-handed helical structure called Z-DNA. For reasons not entirely understood, such dinucleotide repeats in genomic sequences have been associated with genomic instability leading to cancer. Adoption of t...

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Main Authors: Rich, Alexander (Contributor), de Rosa, Matteo (Author), de Sanctis, Daniele (Author), Rosario, Ana Lucia (Author), Archer, Margarida (Author), Athanasiadis, Alekos (Author), Carrondo, Maria Armenia (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences, 2011-03-03T20:20:30Z.
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