mTORC1 Activates SREBP-1c and Uncouples Lipogenesis From Gluconeogenesis
Insulin resistance, which is defined as the inability of insulin to promote efficient glucose uptake by peripheral tissues, is a metabolic condition associated with obesity, type 2 diabetes, dyslipidemia, and cardiovascular diseases. Although important advances in our understanding of the molecular...
Main Authors: | , |
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Other Authors: | , , , |
Format: | Article |
Language: | English |
Published: |
National Academy of Sciences,
2011-03-04T15:39:43Z.
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Subjects: | |
Online Access: | Get fulltext |