Transcript counting in single cells reveals dynamics of rDNA transcription

Most eukaryotes contain many tandem repeats of ribosomal RNA genes of which only a subset is transcribed at any given time. Current biochemical methods allow for the determination of the fraction of transcribing repeats (ON) versus non-transcribing repeats (OFF) but do not provide any dynamical info...

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Bibliographic Details
Main Authors: Tan, Rui Zhen (Author), van Oudenaarden, Alexander (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Physics (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2011-03-14T19:09:54Z.
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