Mutations in Bone Marrow-Derived Stromal Stem Cells Unmask Latent Malignancy

Mutations in Bone Marrow-Derived Stromal Stem Cells Unmask Latent Malignancy

Neoplastic epithelia may remain dormant and clinically unapparent in human patients for decades. Multiple risk factors including mutations in tumor cells or the stromal cells may affect the switch from dormancy to malignancy. Gene mutations, including p53 mutations, within the stroma of tumors are a...

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Bibliographic Details
Main Authors: Houghton, JeanMarie (Author), Li, Hanchen (Author), Fan, Xueli (Author), Liu, Yingwang (Author), Liu, Jian Hua (Author), Rao, Varada P. (Contributor), Poutahidis, Theofilos (Contributor), Taylor, Christie L. (Author), Jackson, Erin A. (Contributor), Hewes, Christine M. (Contributor), Lyle, Stephen (Author), Cerny, Anna (Author), Bowen, Glennice (Author), Cerny, Jan (Author), Moore, Nathan (Author), Kurt-Jones, Evelyn A. (Author), Erdman, Susan E. (Contributor)
Other Authors: Massachusetts Institute of Technology. Division of Comparative Medicine (Contributor)
Format: Article
Language:English
Published: Mary Ann Liebert, 2011-04-22T20:40:40Z.
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