Mutations in Bone Marrow-Derived Stromal Stem Cells Unmask Latent Malignancy
Neoplastic epithelia may remain dormant and clinically unapparent in human patients for decades. Multiple risk factors including mutations in tumor cells or the stromal cells may affect the switch from dormancy to malignancy. Gene mutations, including p53 mutations, within the stroma of tumors are a...
Main Authors: | Houghton, JeanMarie (Author), Li, Hanchen (Author), Fan, Xueli (Author), Liu, Yingwang (Author), Liu, Jian Hua (Author), Rao, Varada P. (Contributor), Poutahidis, Theofilos (Contributor), Taylor, Christie L. (Author), Jackson, Erin A. (Contributor), Hewes, Christine M. (Contributor), Lyle, Stephen (Author), Cerny, Anna (Author), Bowen, Glennice (Author), Cerny, Jan (Author), Moore, Nathan (Author), Kurt-Jones, Evelyn A. (Author), Erdman, Susan E. (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Division of Comparative Medicine (Contributor) |
Format: | Article |
Language: | English |
Published: |
Mary Ann Liebert,
2011-04-22T20:40:40Z.
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Subjects: | |
Online Access: | Get fulltext |
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