Searching for the nik Operon: How a Ligand-Responsive Transcription Factor Hunts for Its DNA Binding Site

Transcription factors regulate a wide variety of genes in the cell and play a crucial role in maintaining cellular homeostasis. A major unresolved issue is how transcription factors find their specific DNA binding sequence in the vast expanse of the cell and how they do so at rates that appear faste...

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Bibliographic Details
Main Authors: Phillips, Christine M. (Contributor), Stultz, Collin M. (Contributor), Drennan, Catherine L. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Massachusetts Institute of Technology. Research Laboratory of Electronics (Contributor)
Format: Article
Language:English
Published: American Chemical Society, 2011-06-30T14:45:26Z.
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