GC-Rich Sequence Elements Recruit PRC2 in Mammalian ES Cells

GC-Rich Sequence Elements Recruit PRC2 in Mammalian ES Cells

Polycomb proteins are epigenetic regulators that localize to developmental loci in the early embryo where they mediate lineage-specific gene repression. In Drosophila, these repressors are recruited to sequence elements by DNA binding proteins associated with Polycomb repressive complex 2 (PRC2). Ho...

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Main Authors: Mendenhall, Eric M. (Author), Koche, Richard Patrick (Contributor), Truong, Thanh (Author), Zhou, Vicky W. (Author), Issac, Biju (Author), Chi, Andrew S. (Author), Ku, Manching (Author), Bernstein, Bradley E. (Author)
Other Authors: Harvard University- (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2011-07-14T17:01:46Z.
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