Utility of Hyaluronan Oligomers and Transforming Growth Factor-Beta1 Factors for Elastic Matrix Regeneration by Aneurysmal Rat Aortic Smooth Muscle Cells

The progression of aortic aneurysms (AAs) is typically associated with an activated smooth muscle cell (SMC) phenotype, diminished density of mature medial elastic fibers, and an elevated presence of matrix-degrading enzymes, which ultimately leads to vessel rupture. Currently, no surgical or nonsur...

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Bibliographic Details
Main Authors: Kothapalli, Chandrasekhar R. (Contributor), Gacchina, Carmen E. (Author), Ramamurthi, Anand (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Mary Ann Liebert, Inc., 2011-07-20T19:05:08Z.
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