Profilin1 regulates PI(3,4)P-2 and lamellipodin accumulation at the leading edge thus influencing motility of MDA-MB-231 cells
Profilin1, a ubiquitously expressed actin-binding protein, plays a critical role in cell migration through actin cytoskeletal regulation. Given the traditional view of profilin1 as a promigratory molecule, it is difficult to reconcile observations that profilin1 is down-regulated in various invasive...
| Main Authors: | , , , , , |
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| Other Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
National Academy of Sciences (U.S.),
2011-07-22T17:03:08Z.
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| Subjects: | |
| Online Access: | Get fulltext |