Integrin alpha 5 beta 1 is necessary for regulation of radial migration of cortical neurons during mouse brain development

Integrin alpha 5 beta 1 is necessary for regulation of radial migration of cortical neurons during mouse brain development

During cerebral cortex development, post-mitotic neurons interact with radial glial fibers and the extracellular environment to migrate away from the ventricular region and form a correct laminar structure. Integrin receptors are major mediators of cell-cell and cell-extracellular matrix interaction...

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Main Authors: Marchetti, Giovanni (Author), Escuin, Sarah (Author), van der Flier, Arjan (Contributor), De Arcangelis, Adele (Author), Georges-Labouesse, Elisabeth (Author), Hynes, Richard O (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Hynes, Richard O. (Contributor)
Format: Article
Language:English
Published: Federation of European Neuroscience Societies and Blackwell Publishing Ltd, 2011-08-11T16:05:47Z.
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