Most mammalian mRNAs are conserved targets of microRNAs

Most mammalian mRNAs are conserved targets of microRNAs

MicroRNAs (miRNAs) are small endogenous RNAs that pair to sites in mRNAs to direct post-transcriptional repression. Many sites that match the miRNA seed (nucleotides 2-7), particularly those in 3' untranslated regions (3'UTRs), are preferentially conserved. Here, we overhauled our tool for...

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Bibliographic Details
Main Authors: Friedman, Robin Carl (Contributor), Farh, Kyle Kai-How (Contributor), Bartel, David (Contributor), Burge, Christopher B (Author)
Other Authors: Harvard University- (Contributor), Massachusetts Institute of Technology. Computational and Systems Biology Program (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor), Burge, Christopher B. (Contributor)
Format: Article
Language:English
Published: Cold Spring Harbor Laboratory Press in association with The Genetics Society, 2011-08-15T18:41:36Z.
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