Multistage nanoparticle delivery system for deep penetration into tumor

Multistage nanoparticle delivery system for deep penetration into tumor

Current Food and Drug Administration-approved cancer nanotherapeutics, which passively accumulate around leaky regions of the tumor vasculature because of an enhanced permeation and retention (EPR) effect, have provided only modest survival benefits. This suboptimal outcome is likely due to physiolo...

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Bibliographic Details
Main Authors: Wong, Cliff (Contributor), Stylianopoulos, Triantafyllos (Author), Cui, Jian (Contributor), Martin, John Daniel (Author), Chauhan, Vikash P. (Author), Jiang, Wen (Author), Popovic, Zoran (Contributor), Jain, Rakesh K. (Author), Bawendi, Moungi G. (Contributor), Fukumura, Dai (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2011-08-15T19:06:56Z.
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