Functional Delivery of siRNA in Mice Using Dendriworms

Functional Delivery of siRNA in Mice Using Dendriworms

Small interfering RNAs (siRNAs) mediate cleavage of specific, complementary mRNA sequences and thus regulate gene expression. Not surprisingly, their use for treatment of diseases that are rooted in aberrant gene expression, such as cancer, has become a paradigm that has gained wide interest. Here,...

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Main Authors: Agrawal, Amit (Contributor), Min, Dal-Hee (Contributor), Singh, Neetu (Contributor), Zhu, Haihao (Author), Birjiniuk, Alona (Contributor), Harris, Todd J. (Contributor), Xing, Deyin (Contributor), Woolfenden, Stephen D. (Contributor), Sharp, Phillip A. (Contributor), Charest, Alain (Contributor), von Maltzhan, Geoffrey (Author), Bhatia, Sangeeta N (Author)
Other Authors: Whitaker College of Health Sciences and Technology (Contributor), Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Bhatia, Sangeeta N. (Contributor), Von Maltzahn, Geoffrey (Contributor)
Format: Article
Language:English
Published: American Chemical Society, 2011-08-23T15:36:31Z.
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