The EHEC Type III Effector NleL Is an E3 Ubiquitin Ligase That Modulates Pedestal Formation

Enterohemorrhagic Escherichia coli (EHEC) O157:H7 causes hemorrhagic colitis and may result in potentially fatal hemolytic uremia syndrome in humans. EHEC colonize the intestinal mucosa and promote the formation of actin-rich pedestals via translocated type III effectors. Two EHEC type III secreted...

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Bibliographic Details
Main Authors: Piscatelli, Heather (Author), Kotkar, Shalaka A. (Author), McBee, Megan E. (Contributor), Muthupalani, Sureshkumar (Contributor), Schauer, David B. (Contributor), Mandrell, Robert E. (Author), Leong, John M. (Author), Zhou, Daoguo (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Division of Comparative Medicine (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2011-08-26T15:12:26Z.
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